Mail does have "run Applescript" in the list of available actions in Prefs -> Rules (a.k.a. Filters). You can also add headers to the list available, so it would be quite easy to specify custom headers in different types of incoming mail if you wanted to be able to control more choices than just "it's from X".

Thankyou to winwintoo for bringing up the access question again: I've been very ill and disabled for years now, and among user groups for people who are dealing with multiple disabilities, user interface is a huge issue: even Mail can defeat people who need to be able to access such lists/sites. Something very simple, to reduce the amount of info on the screen, and make the main choices very big and very clear and very easy to input, would make things much easier for people for whom a computer is truly a window on the world.

Does anyone know if any developers are working on ways to simplify computer use for ill/disabled people? I would appreciate any info/links.

Your mother sounds like a wonderful person, winwintoo, I respect her greatly for her willingness to take on so much new information, and her evident zest for life. :)

from Clytie, for whom everything is fogging out again now